The Journal of Toxicological Sciences

Top 10 papers by download from our web site


March 2026

1. 528 times
Characterization of air freshener emission: the potential health effects
Sanghwa Kim, Seong-Ho Hong, Choon-Keun Bong, Myung-Haing Cho
J. Toxicol. Sci., 40: 535-550

2.440 times
Prolonged toxicity after massive olanzapine overdose: two cases with confirmatory laboratory data
George H. Tse, Maria H. Warner, W. Stephen Waring
J. Toxicol. Sci., 33: 363-365

3.303 times
Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan)
Mariko Sugiyama, Masaharu Akita, Nathalie Alépée, Miyuki Fujishiro, Shigenobu Hagino, Yuki Handa, Hidefumi Ikeda, Noriyasu Imai, Setsuko Jitsukawa, Masakazu Katoh, Koji Kurihara, Daiki Kyotani, Shigeyuki Nomura, Yuko Okamoto, Hidenobu Okumura, Takashi Omori, Kenji Sugibayashi, Hiroaki Todo, Akemi Toyoda, Yasuo Ohno
J. Toxicol. Sci., 43: 751-768

4.235 times
Human erythropoietin mRNA as an impurity from a mRNA-LNP vaccine induces immune-mediated anemia in rats
Yukie Murata, Shingo Kitamura, Yoshiji Asaoka, Shun Kitahata, Keisaku Wakabayashi, Hidetoshi Kouno, Norikazu Kuroda, Kayo Ishida, Shinobu Miki, Takafumi Sato, Osamu Yoshida, Akira Kugimiya, Tomokazu Yoshinaga, Tamio Fukushima
J. Toxicol. Sci., 51: 201-213

5.225 times
Spermidine alleviates sepsis-induced acute kidney injury by suppressing apoptosis and inflammation through modulation of TLR4-mediated signaling
Yun Shen, Qinyi Shi, Ting Dai, Yi Cai, Mengting Sheng, Ying Qiu, Ming Yang, Sanhong Hu, Bo Cheng
J. Toxicol. Sci., 50: 555-567

6.222 times
Neurotoxicity of acrylamide in wild-type and TNF-α depletion mice: possible alternative role of IL-6 and dipolar effects of TNF-α depletion on oxidative stress pathway
Cai Zong, Harue Sato, Sahoko Ichihara, Yoichiro Iwakura, Seiichiroh Ohsako, Gaku Ichihara
J. Toxicol. Sci., 51: 183-199

6.222 times
A zwitterionic solvent for in vitro toxicity tests of insoluble compounds
Yusuke Kubota, Ayako Hohsaka, Eishu Hirata, Kosuke Kuroda
J. Toxicol. Sci., 51: 227-237

8.219 times
Comprehensive molecular docking on the AlphaFold-predicted protein structure proteome: identifying target protein candidates for puberulic acid
Teppei Hayama, Rin Sugawara, Ryo Kamata, Masakazu Sekijima, Kazuki Takeda
J. Toxicol. Sci., 50: 309-324

9.208 times
Effects of perfluorooctane sulfonate (PFOS) on cognitive behavior and autophagy of male mice
Aojia Zhou, Li Wang, Xuejiao Pi, Cheng Fan, Wenwen Chen, Ziping Wang, Shuang Rong, Ting Wang
J. Toxicol. Sci., 48: 513-526

10.204 times
Per- and polyfluoroalkyl substances: toxicokinetics, exposure and health risks
Yukiko Fujii, Kouji H. Harada
J. Toxicol. Sci., 50: 97-104


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology