The Journal of Toxicological Sciences

Top 10 papers by download from our web site


January 2022

1. 155 times
Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis
Shu Dong, Qi-Long Chen, Ya-Nan Song, Yang Sun, Bin Wei, Xiao-Yan Li, Yi-Yang Hu, Ping Liu, Shi-Bing Su
J. Toxicol. Sci., 41: 561-572

2. 128 times
HepG2-NIAS cells, a new subline of HepG2 cells that can enhance not only CYP3A4 activity but also expression of drug transporters and form bile canaliculus-like networks by the oxygenation culture via a collagen vitrigel membrane
Toshiaki Takezawa, Miaki Uzu
J. Toxicol. Sci., 47: 39-50

3. 119 times
Development challenges for carcinogenicity risk assessments of topical drugs
Brett D Hollingshead, Nasir Khan, Maik Schuler, Zaher Radi
J. Toxicol. Sci., 47: 1-11

4. 106 times
Characterization of air freshener emission: the potential health effects
Sanghwa Kim, Seong-Ho Hong, Choon-Keun Bong, Myung-Haing Cho
J. Toxicol. Sci., 40: 535-550

5. 98 times
A novel perfusion culture system for screening mitochondrial toxicity in primary mouse hepatocytes
Chika Yamamoto, Akinori Takemura, Sanae Ishii, Atsushi Doi, Isao Saito, Hideki Yamada, Yoko Sakai, Tamihide Matsunaga, Kousei Ito
J. Toxicol. Sci., 47: 13-18

6. 93 times
Spatio-temporal distribution of reactive sulfur species during methylmercury exposure in the rat brain
Takamitsu Unoki, Masahiro Akiyama, Yasuhiro Shinkai, Yoshito Kumagai, Masatake Fujimura
J. Toxicol. Sci., 47: 31-37

7. 86 times
Macrophage differentiation induced by PMA is mediated by activation of RhoA/ROCK signaling
Lifeng Yang, Fan Dai, Lian Tang, Yulan Le, Wenjuan Yao
J. Toxicol. Sci., 42: 763-771

8. 78 times
Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing
Jeffrey C. Raber, Sytze Elzinga, Charles Kaplan
J. Toxicol. Sci., 40: 797-803

9. 65 times
Acyl-CoA:diacylglycerol acyltransferase 1 inhibition in the small intestine increases plasma transaminase activity via the activation of protein kinase C pathway
Hideaki Yokoyama, Taku Masuyama, Yuki Tanaka, Iori Tsubakihara, Kazuma Kondo, Kouichi Yoshinari
J. Toxicol. Sci., 47: 19-30

10. 63 times
Gene expression profiling of cultured mouse testis fragments treated with ethinylestradiol
Noriko Nakamura, Daniel T. Sloper, Pedro L. Del Valle
J. Toxicol. Sci., 44: 667-679


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology