The Journal of Toxicological Sciences

Top 10 papers by download from our web site


January 2023

1. 189 times
Establishment of an in vitro cholestasis risk assessment system using two-dimensional cultured HepaRG cells and 12 bile acids
Toshihisa Koga, Kenji Takeuchi, Ken Umehara
J. Toxicol. Sci., 48: 47-56

2. 142 times
Species differences in activation of TRPA1 by resin additive-related chemicals relevant to indoor air quality
Yoko Mori, Toshiko Tanaka-Kagawa, Maiko Tahara, Tsuyoshi Kawakami, Akira Aoki, Yoshinori Okamoto, Takashi Isobe, Susumu Ohkawara, Nobumitsu Hanioka, Kenichi Azuma, Shinobu Sakai, Hideto Jinno
J. Toxicol. Sci., 48: 37-45

3. 139 times
Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells
Miyu Kamimura, Azusa Sasaki, Yui Otani, Yasushi Nakamura, Takako Nakamura, Kouji Kuramochi, Toshio Imai, Nakao Kubo, Shigehisa Okamoto
J. Toxicol. Sci., 48: 25-35

3. 127 times
Effect of microsampling (50 L) on toxicological evaluation of methapyrilene, a hepatotoxic substance, in a collaborative 28-day study in female rats
Norimichi Hattori, Hideaki Yokoyama, Asuka Takumi, Sayaka Kawaguchi, Koki Yamaguchi, Taishi Shimazaki, Yusuke Shibui, Kosuke Saito, Yoshiro Saito
J. Toxicol. Sci., 48: 1-14

5. 119 times
Characterization of air freshener emission: the potential health effects
Sanghwa Kim, Seong-Ho Hong, Choon-Keun Bong, Myung-Haing Cho
J. Toxicol. Sci., 40: 535-550

6. 114 times
Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis
Shu Dong, Qi-Long Chen, Ya-Nan Song, Yang Sun, Bin Wei, Xiao-Yan Li, Yi-Yang Hu, Ping Liu, Shi-Bing Su
J. Toxicol. Sci., 41: 561-572

7. 112 times
Rapid derivatization of phosphorus-containing amino acid herbicides in plasma and urine using microwave heating
Hiroyuki Mohri, Kazuko Mohri, Akinaga Gohda, Yuji Ishii
J. Toxicol. Sci., 48: 15-24

8. 72 times
Toxicological effects of propofol abuse on the dopaminergic neurons in ventral tegmental area and corpus striatum and its potential mechanisms
Qi Chen, Shurong Li, Yuping Han, Xiaohong Wei, Juan Du, Xiaolin Wang, Bingyin Su, Jun Li
J. Toxicol. Sci., 45: 391-399

9. 67 times
Establishment of a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish
Naoteru Koseki, Jiro Deguchi, Akihito Yamashita, Izuru Miyawaki, Hitoshi Funabashi
J. Toxicol. Sci., 39: 579-600

10. 66 times
Development challenges associated with rAAV-based gene therapies
Michael W. Bolt, Joseph T. Brady, Lawrence O. Whiteley, K. Nasir Khan
J. Toxicol. Sci., 46: 57-68


The Journal of Toxicological Sciences (J. Toxicol. Sci.) published by The Japanese Society of Toxicology